发明名称 |
IMPROVED PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS |
摘要 |
Novel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids are disclosed. Particularly, novel methods for efficiently preparing compounds having a glycerolic backbone and one or more oxidized moieties attached to the glycerolic backbone, which are devoid of column chromatography are disclosed. Further disclosed are novel methods of introducing phosphorous-containing moieties such as phosphate moieties to compounds having glycerolic backbone and intermediates formed thereby. |
申请公布号 |
CA2844908(A1) |
申请公布日期 |
2008.07.17 |
申请号 |
CA20082844908 |
申请日期 |
2008.01.02 |
申请人 |
VASCULAR BIOGENICS LTD. |
发明人 |
HALPERIN, GIDEON;KOVALEVSKI-ISHAI, ETI |
分类号 |
C07C67/31;C07B41/00;C07F9/02 |
主分类号 |
C07C67/31 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|