CSF BIOMARKERS FOR THE PREDICTION OF COGNITIVE DECLINE IN ALZHEIMER'S DISEASE PATIENTS
摘要
The present invention provides a method for predicting the short-term and long-term cognitive decline in Alzheimers disease patients and uses thereof in predicting efficacy of an AD therapeutic. The method uses baseline levels of CSF biomarkers to predict decreases over time in CAMCOG and MMSE scores.
申请公布号
CA2731247(A1)
申请公布日期
2010.01.28
申请号
CA20092731247
申请日期
2009.07.16
申请人
MERCK SHARP & DOHME CORP.;ISIS INNOVATION LIMITED
发明人
SEEBURGER, JEFFREY L.;HOLDER, DANIEL J.;SMITH, DAVID A.;OULHAJ, ABDERRAHIM