发明名称 Substituted prolines / piperidines as orexin receptor antagonists
摘要 Disclosed herein are compounds of formula I where the substituents are as defined herein that can modulate the bioactivity of an orexin receptor such as OX1 or OX2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention.
申请公布号 NZ628491(A) 申请公布日期 2016.06.24
申请号 NZ20130628491 申请日期 2013.02.06
申请人 EOLAS THERAPEUTICS INC. 发明人 KAMENECKA THEODORE;JIANG RONG;SONG XINYI
分类号 A61K31/40;A61K31/445 主分类号 A61K31/40
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