| 主权项 |
1. A method using one or more indicators of glycemic health in a patient to balance one or more of hypoglycemic or hyperglycemic tendencies for the patient, the method comprising:
at a special purpose computing apparatus, computing a profile of a blood glucose concentration of the patient based, at least in part, on observations of the blood glucose concentration collected at a blood glucose monitoring device; applying a cost or loss function to the computed profile to compute a metric for balancing short-term and long-term risks associated with a therapy, the metric representative of the glycemic health of the patient, the cost or loss function being based, at least in part, on a log-square metric, wherein the metric is also based, at least in part, on a parameter selected to balance one or more Spearman rank coefficients with one or more hypoglycemic-based metrics and one or more hyperglycemic-based metrics; and altering an insulin therapy applied to the patient by an infusion device, the altered insulin therapy determined based, at least in part, on the computed metric, wherein the altered insulin therapy is also based, at least in part, on a target blood glucose concentration level or target blood glucose range that has been adjusted upward or downward based, at least in part, on an indication by the computed metric of whether the patient is tending towards hypoglycemia or tending towards hyperglycemia. |
