发明名称 Central nervous system transcription regulator polypeptide and a DNA sequence to which a protein containing the polypeptide binds
摘要 The present invention provides a polypeptide which is common to essentially all proteins expressed by the glial cells missing (gcm) gene, which is a fate determination gene of animal central nervous system cells, said polypeptide having the amino acid sequence of Sequence ID No. 1 or a part, functional fragment, derivative, homologue or analogue, thereof and a DNA sequence to which proteins containing the polypeptide binds. The polypeptide and DNA sequence bound by the polypeptide facilitate study and clarification of the mechanisms by which the human nervous system is formed and opens up new ways to develop diagnostic and medical treatment regimes for cerebral functional diseases and cerebral tumours.
申请公布号 EP0855442(A2) 申请公布日期 1998.07.29
申请号 EP19970309637 申请日期 1997.11.28
申请人 JAPAN SCIENCE AND TECHNOLOGY CORPORATION 发明人 HOTTA, YOSHIKI
分类号 C12N15/09;A61K38/00;A61P25/00;A61P35/00;C07H21/04;C07K14/435;C07K14/47;C12N1/21;C12N15/12;C12Q1/68 主分类号 C12N15/09
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