| 发明名称 |
SULFONYLAMINO DERIVATIVES WHICH INHIBIT MATRIX-DEGRADING METALLOPROTEINASES |
| 摘要 |
Compounds of formula (I) wherein W is -OH or -NHOH; X is an optionally substituted heterocycle, NR1SO2R2, heterocyclylalkythio, CONR2R3 or NR1COR2; Y, Z, R1-R3 and n are as defined in the application. Compounds (I) are inhibitors of matrix-degrading metalloproteinases and are use for the treatment of related conditions.
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| 申请公布号 |
CA2318145(A1) |
申请公布日期 |
1999.08.26 |
| 申请号 |
CA19992318145 |
申请日期 |
1999.02.02 |
| 申请人 |
NOVARTIS AG |
发明人 |
NAKAJIMA, MOTOWO;SAKAKI, JUNICHI;ROBINSON, LESLIE ANNE;KUKKOLA, PAIVI JAANA |
| 分类号 |
C07D295/18;A61K31/18;A61K31/403;A61K31/4035;A61K31/4166;A61K31/4184;A61K31/428;A61K31/437;A61K31/4439;A61K31/4453;A61K31/454;A61K31/517;A61K31/5375;A61P9/00;A61P9/10;A61P19/02;A61P25/00;A61P27/02;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07C311/19;C07C311/27;C07D209/48;C07D233/74;C07D239/96;C07D275/06;C07D417/12;C07D417/14;C07D471/04;(IPC1-7):C07D209/48;A61K31/40;A61K31/415;A61K31/425;A61K31/505 |
主分类号 |
C07D295/18 |
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