发明名称 |
Influenza Nucleic Acid Molecules And Vaccines Made Therefrom |
摘要 |
Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of HA Influenza A of serotype H7N9 alone and in combination with HA hemagglutinin and/or influenza B hemagglutinin, as well as genetic constructs/vectors and vaccines expressing the sequences. Also provided herein are methods for generating an immune response against one or more influenza A serotypes and/or influenza B serotypes, or combinations thereof, using the vaccines that are provided. |
申请公布号 |
US2016175427(A1) |
申请公布日期 |
2016.06.23 |
申请号 |
US201414910136 |
申请日期 |
2014.08.04 |
申请人 |
WEINER David;YAN Jian;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA ;INOVIO PHARMACEUTICALS, INC. |
发明人 |
Weiner David B.;Yan Jian |
分类号 |
A61K39/145;C12N7/00;C07K14/005 |
主分类号 |
A61K39/145 |
代理机构 |
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代理人 |
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主权项 |
1. An isolated nucleic acid comprising a nucleic acid sequence encoding an amino acid sequence selected from the group consisting of SEQ ID NO: 40, an amino acid sequence that is 95% identical over the entire length of the amino acid sequence of SEQ ID NO: 40, a fragment of SEQ ID NO: 40 comprising at least 30 amino acids, and an amino acid sequence that is 95% identical to a fragment of SEQ ID NO: 40 comprising at least 30 amino acids. |
地址 |
Merion PA US |