发明名称 |
METHODS AND COMPOSITIONS USING LISTERIA FOR ENHANCING IMMUNOGENICITY BY PRIME BOOST |
摘要 |
Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response. |
申请公布号 |
US2016175415(A1) |
申请公布日期 |
2016.06.23 |
申请号 |
US201514952281 |
申请日期 |
2015.11.25 |
申请人 |
ADURO BIOTECH, INC. |
发明人 |
Dubensky, JR. Thomas W.;Brockstedt Dirk G.;Leong Meredith Lai Ling;Bahjat Keith S. |
分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Berkeley CA US |