| 摘要 |
The novel compound of the formula <IMAGE> and its pharmaceutically acceptable salts are prepared by culturing an appropriate strain of Streptomyces flavogriseus in aqueous nutrient medium which contains assimilable sources of carbon, nitrogen and inorganic salts, under submerse, aerobic conditions and recovering the antibiotic formed. The novel antibiotic is active against various gram-positive and -negative bacteria and is a potent inhibitor of bacterial beta -lactamases. It can be used in human and veterinary medicine and is also suitable as an additive to animal feed owing to preservation of feedstuffs and foodstuffs, and as a disinfectant. |
