Dihydropyridine combination product comprising a dihydropyridine compound and a cardioactive nitrate

摘要

A solid medicament formulation which can be administered orally, comprising 1 to 40 mg of a dihydropyridine of the formula <IMAGE> in which R1 and R3 are always different from one another and represent alkyl which has 1 to 12 carbon atoms and which is optionally substituted once or several times by fluorine or chlorine or which is optionally interrupted by an oxygen atom in the chain, and A represents the radical <IMAGE> R2 representing one or two substituents from the group consisting of nitro, chlorine and trifluoromethyl, or represents <IMAGE> and 0.1 to 100 mg of a cardioactive nitrate. The composition is cardio-active and the patient's tendency toward nitrate tolerance is reduced.