| 发明名称 |
Acyclic metalloprotease inhibitors |
| 摘要 |
The invention provides compounds of formulaas described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of metalloproteases.Also disclosed are pharmaceutical compositions and methods of treating diseases, disorders and conditions characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them. |
| 申请公布号 |
ZA9806835(B) |
申请公布日期 |
1999.02.01 |
| 申请号 |
ZA19980006835 |
申请日期 |
1998.07.30 |
| 申请人 |
THE PROCTER & GAMBLE COMPANY. |
发明人 |
NEIL GREGORY ALMSTEAD;ROGER GUNNARD BOOKLAND;YETUNDE OLABISI TAIWO;RIMMA SANDLER BRADLEY;RODNEY DEAN BUSH;BISWANATH DE;MICHAEL GEORGE NATCHUS;STANISLAW PIKUL |
| 分类号 |
C07D295/18;A61K31/18;A61K31/215;A61K31/351;A61K31/382;A61K31/4035;A61K31/4166;A61K31/426;A61K31/4406;A61K31/445;A61K31/455;A61K31/495;A61K31/5375;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P7/00;A61P7/02;A61P7/08;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P15/04;A61P15/08;A61P17/02;A61P17/14;A61P17/16;A61P19/00;A61P19/02;A61P19/10;A61P21/00;A61P21/04;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/12;A61P31/16;A61P31/18;A61P31/22;A61P33/00;A61P35/02;A61P37/00;A61P37/06;A61P39/00;A61P43/00;C07C259/06;C07C311/14;C07C311/19;C07C311/29;C07C317/48;C07C323/60;C07C323/61;C07D207/40;C07D207/412;C07D209/48;C07D211/54;C07D211/84;C07D213/56;C07D213/82;C07D233/74;C07D277/20;C07D277/44;C07D277/46;C07D277/52;C07D295/20;C07D309/08;C07D335/02;C07F9/36 |
主分类号 |
C07D295/18 |
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