VINCA-ALKALOID VESICLES WITH ENHANCED EFFICACY AND TUMOR TARGETING PROPERTIES

摘要

A liposome formulation containing a vinca alkaloid and an anion in an aqueou s phase of the liposome. The liposomes also comprise distearoylphosphatidyl choline, cholesterol and distearoylphosphatidylglycer ol. A method for enhancing the efficacy and tumor target ing properties of liposomal vinca alkaloid formulations containing unilamellar v esicles.