发明名称 METHOD OF TREATING OR PREVENTING INFERTILITY IN A FEMALE MAMMAL AND PHARMACEUTICAL KIT FOR USE IN SUCH METHOD
摘要 The present invention relates to a method of treating infertility in a fe male mammal that involves controlled ovarian hyperstimulation, said method c omprising administering to said female mammal a combination of (i) an FSH su bstance in an amount effective to stimulate follicular development and (ii) a steroid in an effective amount to inhibit or suppress the secretion of lut einising hormone, said steroid being selected from the group consisting of: substances represented by the following formula (I) in which formula R1, R2, R3, R4 independently are a hydrogen atom, a hydroxyl group or an alkoxy gro up with 1 -5 carbon atoms; each of R5, R6,R7 is a hydroxyl group; no more th an 3 of R1, R2, R3, R4 are hydrogen atoms; derivatives of the aforementioned steroid substances; and mixtures of one or more of the aforementioned subst ances and/or derivatives.
申请公布号 CA2674325(A1) 申请公布日期 2008.07.17
申请号 CA20082674325 申请日期 2008.01.07
申请人 PANTARHEI BIOSCIENCE B.V. 发明人 COELINGH BENNINK, HERMAN JAN TIJMEN
分类号 A61K31/565;A61P15/08 主分类号 A61K31/565
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