发明名称 |
ADENOSINE DERIVATIVES, METHOD FOR THE SYNTHESIS THEREOF, AND THE PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE INFLAMMATORY DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT |
摘要 |
Disclosed are adenosine derivatives, methods for the synthesis thereof, and pharmaceutical compositions for the prevention and treatment of inflammatory diseases, comprising the same as an active ingredient. The adenosine derivatives have high binding affinity and selectivity for adenosine receptors, especially for A3 adenosine receptors and act as A3 adenosine receptor antagonists, and exhibit anti-inflammatory activity. Thus, the adenosine derivatives are useful in the prevention and treatment of inflammatory diseases. |
申请公布号 |
WO2008108508(A1) |
申请公布日期 |
2008.09.12 |
申请号 |
WO2007KR01131 |
申请日期 |
2007.03.07 |
申请人 |
FM THERAPEUTICS CO., LTD.;JEONG, LAK SHIN;KIM, HEA OK;JACOBSON, KENNETH A.;CHOE, SEUNG AH |
发明人 |
JEONG, LAK SHIN;KIM, HEA OK;JACOBSON, KENNETH A.;CHOE, SEUNG AH |
分类号 |
C07D473/34;A61K31/4985 |
主分类号 |
C07D473/34 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|