发明名称 AROMATIC CARBOXYLIC AMIDES
摘要 The compounds of the general formula …<IMAGE>… in which R<1> is hydrogen, halogen or OR<5>; R<2> is hydrogen, lower alkyl, lower alkoxy or halogen; R<3> and R<4> independently of one another are lower alkyl; or together are straight-chain alkylene having 3 to 5 C atoms; R<5> is hydrogen, acyl, lower alkoxycarbonyl or lower alkyl which can be substituted by amino, mono- or dialkylamino or by a radical -N-Het; -N-Het is a 5-8-membered saturated or unsaturated monocyclic heterocycle which is bonded via an N atom; and M is -CONH- or -NHCO-,… can be used as medicaments, for example for treating neoplasia and dermatological indications of inflammatory and allergic nature.
申请公布号 ZA9005738(B) 申请公布日期 1991.03.27
申请号 ZA19900005738 申请日期 1990.07.20
申请人 F. HOFFMANN-LA ROCHE A.G. 发明人 MICHAEL KLAUS;PETER MOHR
分类号 A61K31/165;A61K31/415;A61K31/495;A61K31/535;A61K31/5375;A61P35/00;A61P37/00;C07C231/02;C07C233/64;C07C233/65;C07C233/66;C07C233/73;C07C233/75;C07C235/56;C07C235/64;C07D233/64;C07D295/08;C07D295/088;C07D295/092;C07D521/00 主分类号 A61K31/165
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