发明名称 LIVE ATTENUATED VACCINES
摘要 An attenuated bacterium in which the native fur gene, or homologue thereof, is modified such that the expression of the fur gene product, or homologue thereof, is regulated independently of the iron concentration in the environment of the bacterium, is suitable for use as a live vaccine. The bacterium may be, in particular, Neisseria meningitidis.
申请公布号 WO9856901(A2) 申请公布日期 1998.12.17
申请号 WO1998GB01683 申请日期 1998.06.09
申请人 MEDICAL RESEARCH COUNCIL;BALDWIN, THOMAS, JOHN;BORRIELLO, SAVERIO, PETER;PALMER, HELEN, MARY 发明人 BALDWIN, THOMAS, JOHN;BORRIELLO, SAVERIO, PETER;PALMER, HELEN, MARY
分类号 C12N15/09;A61K39/00;A61K39/095;A61K39/10;A61K39/102;A61K39/104;A61K39/108;A61K39/112;A61P31/04;C07K14/22;C12N1/20;C12N1/21;C12R1/36 主分类号 C12N15/09
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