PLASMINOGEN ACTIVATOR AS AN ANTI-INFLAMMATORY AGENT
摘要
Plasminogen activator acts as an anti-inflammatory agent by inhibiting generation of superoxide anion by a mechanism that is not related to L-arginine, is not dependent on thrombolytic activity, and is not a function of oxygen free radical scavenging. Moreover, in in vivo models of inflammation, treatment with plasminogen activator reduces edema without inhibiting neutrophil infiltration in in vivo models of inflammation.
申请公布号
WO9832459(A1)
申请公布日期
1998.07.30
申请号
WO1998US01948
申请日期
1998.01.29
申请人
UNIVERSITY TECHNOLOGY CORPORATION;STRINGER, KATHLEEN, A.;HYBERTSON, BROOKS, M.;REPINE, JOHN, E.;MCCORD, JOE, M.
发明人
STRINGER, KATHLEEN, A.;HYBERTSON, BROOKS, M.;REPINE, JOHN, E.;MCCORD, JOE, M.