| 发明名称 |
SUBSTITUTED PYRIMIDINE BMI-1 INHIBITORS. |
| 摘要 |
Amine substituted pyrimidine compounds and forms thereof that inhibit the function and reduce the level of B -cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein and methods for their use to inhibit Bmi-1 function and reduce the level of Bmi-1 to treat a cancer mediated by Bmi-1 are described herein. |
| 申请公布号 |
MX2016002642(A) |
申请公布日期 |
2016.08.12 |
| 申请号 |
MX20160002642 |
申请日期 |
2013.11.21 |
| 申请人 |
PTC THERAPEUTICS, INC. |
发明人 |
Chang-Sun LEE;Ramil BAIAZITOV;Wu DU;Hongyu REN;Nadiya SYDORENKO;Young-Choon MOON;Steven, D. PAGET;Richard, Gerald WILDE |
| 分类号 |
C07D239/48 |
主分类号 |
C07D239/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
