| 发明名称 |
UNSATURATED HYDROXYALKYLQUINOLINE ACIDS AS LEUKOTRIENE ANTAGONISTS |
| 摘要 |
<p>Compounds having the formula I: <CHEM> are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.</p> |
| 申请公布号 |
LV12187(B) |
申请公布日期 |
1999.02.20 |
| 申请号 |
LV19980000153 |
申请日期 |
1998.07.23 |
| 申请人 |
MERCK FROSST CANADA INC. |
发明人 |
BELLEY,MICHEL L.;LEGER,SERGE;ROY,PATRICK;YI BIN,XIANG;LABELLE,MARC;GUAY,DANIEL |
| 分类号 |
A61K31/47;A61K31/41;A61P9/00;A61P11/00;A61P11/06;A61P11/10;A61P13/02;A61P15/00;A61P27/02;A61P27/14;A61P27/16;A61P29/00;A61P29/02;A61P37/08;A61P43/00;C07D;C07D215/00;C07D215/12;C07D215/14;C07D215/18;C07D215/48;C07D401/00;C07D401/12;(IPC1-7):C07D215/18 |
主分类号 |
A61K31/47 |
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