CYTOTOXICITY MEDIATION OF CELLS EVIDENCING SURFACE EXPRESSION OF CD59
摘要
<p>This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumour cells evidencing surface expression of CD59, and to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response The invention further relates to binding assays which utilize the CDMAB of the instant invention.</p>
申请公布号
WO2007095747(A1)
申请公布日期
2007.08.30
申请号
WO2007CA00280
申请日期
2007.02.22
申请人
ARIUS RESEARCH, INC.;YOUNG, DAVID S.F.;FINDLAY, HELEN, P.;HAHN, SUSAN, E.;CECHETTO, LISA, M.;DACRUZ, LUIS, A. G.
发明人
ARIUS RESEARCH, INC.;YOUNG, DAVID S.F.;FINDLAY, HELEN, P.;HAHN, SUSAN, E.;CECHETTO, LISA, M.;DACRUZ, LUIS, A. G.