METHOD OF PREDICTING PROTEIN ALLERGENICITY USING A SUPPORT VECTOR MACHINE

摘要

A method for predicting the allergenicity of a protein using a non-linear prediction model based on an algorithm such as a probabilistic function, artificial neural network, hidden Markov model, multiple regression or Bayesian network, and in particular a support vector machine. The method comprises a learning phase where a data set of allergenic proteins is used to train the prediction model, and a prediction phase where the allergenicity of a protein is determined using the trained prediction model. In one embodiment the support vector machine is trained by creating a hyperplane separating and classifying the training examples according to a kernel function, where a third degree polynomial kerne function was optimal.