发明名称 |
METHODS FOR CHRONIC PAIN MANAGEMENT AND TREATMENT USING HCG |
摘要 |
A gonadotropin is administered within a surprisingly effective narrow range for the purpose of treating chronic pain or other central sensitization sequelae. In one aspect, a recipient is provided with at least one of human chorionic gonadotropin (uHCG and /or rHCG), a pharmaceutically active HCG analogue, and a pharmaceutically active metabolite of the HCG or analogue at a dosage selected to provide an amount therapeutically bioequivalent to, a human subcutaneous dosage of between 120 IU/day and 170 IU/day of HCG, and more preferably between 140 IU/day and 160 IU/day of HCG. A combination product is also described, which includes a supply of the HCG-related drug, a delivery device, and a conversion scale for therapeutic bioequivalence that identifies the specific amount and route of administration for chronic pain or central sensitization as an indication of the drug. |
申请公布号 |
WO2016077565(A3) |
申请公布日期 |
2016.06.30 |
申请号 |
WO2015US60348 |
申请日期 |
2015.11.12 |
申请人 |
NEURALIGHT HD, LLC;HICKS, JR., EDSON CONRAD;DUTTON, CONSTANCE T. |
发明人 |
HICKS, JR., EDSON CONRAD;DUTTON, CONSTANCE T. |
分类号 |
A61K38/24;A61P43/00 |
主分类号 |
A61K38/24 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|