System and method for quantitative analysis of respiratory sinus arrhythmia

摘要

A computer-assisted method for quantitative analysis of respiratory sinus arrhythmia (RSA) includes obtaining a time series of a cardiac interval signal from an individual, obtaining a time series of a respiratory signal from the individual; decomposing the cardiac interval signal into a first group of ensemble empirical modes; obtaining, by a computer system, a time series of RSA instantaneous amplitude from at least one of the first group of ensemble empirical modes; decomposing the respiratory signal into a second group of ensemble empirical modes; obtaining a time series of respiratory instantaneous phase from the one of the second group of ensemble empirical modes; determining respiratory period from the time series of the respiratory instantaneous phase; and quantifying RSA in the individual according to a dependence of the RSA instantaneous amplitude on the respiratory period.

主权项

1. A computer-assisted method for quantitative analysis of respiratory sinus arrhythmia (RSA), comprising:
obtaining a time series of a cardiac interval signal from an individual using a first probe; obtaining a time series of a respiratory signal from the individual using a second probe; receiving the time series of the cardiac interval signal and the time series of the respiratory signal by an analyzer in connection with the first probe and the second probe; decomposing the cardiac interval signal into a first group of ensemble empirical modes using the analyzer; obtaining, by a computer system in the analyzer, a time series of RSA instantaneous amplitude from at least one in the first group of ensemble empirical modes; decomposing the respiratory signal into a second group of ensemble empirical modes; obtaining a time series of respiratory instantaneous phase from one of the second group of ensemble empirical modes; determining respiratory period from the time series of the respiratory instantaneous phase; quantifying RSA in the individual at least in part according to a dependence of the RSA instantaneous amplitude on the respiratory period, and displaying a graphic pattern on a respiratory feedback device in communication with the analyzer, wherein the graphic pattern shows dependence of the RSA instantaneous amplitude on the respiratory period, wherein the individual adjusts a breathing pattern to maximize amplitude of the graphic pattern and closeness to a goal of the graphic pattern to improve respiratory functions of the individual.