发明名称 PROCEDIMIENTO PARA LA PREPARACION DE UNA COMPOSICION DE E- FECTO ANTIDEPRESIVA.
摘要 <p>Anti depressant compositions which increase the 5-hydroxytryptophane concentration. M3A. Comprise tryptophane in its laevorotatory form and one or more of pyridoxal phosphate, of ascorbic acid and of a sugar favouring assimilation and optionally a small amount of foic acid. The compositions may be administered as a suspending tablet or as granules; the unit dose being 0.1 to 3g% laevorotatory tryptophane. Aqueous solutions may also contain one or more of glycerol, glycerol monoleate, sodium benzoate, sodium metabisulphite, a tartrazine liqueur and an aromatic agent. Capsules pref. contain aromatic agents, sodium metabisulphite and mannitol as the sugar. Other suitable sugars are dextrose, glucose and D-sorbitol. Suitable precursors of pyridoxal phosphate are pyridoxine, pyridoxal and pyridoxamine. Other adjuvants which facilitate the assimilation, hydroxylation and decarboxylation of laevorotatory tryptophane to 5-hydroxy - tryptophane may also be present.</p>
申请公布号 ES372150(A1) 申请公布日期 1971.12.16
申请号 ES19500003721 申请日期 1969.10.03
申请人 CAMBRIAN CHEMICALS LIMITED 发明人
分类号 A61K31/44;A61K31/445;A61K31/505;A61K31/70;(IPC1-7):61K/ 主分类号 A61K31/44
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