| 摘要 |
NEW MATERIAL:A physiologically active substance, NSH extracted from tissues with poxes. USE:Tranquilizer, autonomic controller, sedative and antiulcerative: it is applied to various kinds of diseases caused by stresses and autonomic imbalance. The combination with other medicines reduces its side-effects and gives an expectation of synergism. PREPARATION:Sterilely collected tissues with poxes are ground, combined with phenol-water in an amount of 1-5 times that of the tissue to form a milk-like substance, then subjected to filtration or centrifugation. The resultant solution is adjusted in pH near its isoelectric point, heated, filtered to remove protein and made acidic with a mineral acid, then adsorbed on 5-20% activated carbon. The activated carbon is combined with an aqueous alkali to adjust its pH to 10-12 and exudation is effected under heating. The exudate is evaporated to dryness under reduced pressure or freeze dried to give the objective physiologically active substance, NSH. |
