发明名称 TRICYCLIC DERIVATIVES AND THEIR USE IN PHARMACEUTICALS
摘要 Disclosed are compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein: R<4> is alkenyl, alkoxy, or -OH. Also disclosed are pharmaceutical compositions containing compounds of formula (I), methods for inhibiting tumor necrosis factor- alpha , and methods for treating septic shock, inflammation, or allergic disease.
申请公布号 WO9515959(A1) 申请公布日期 1995.06.15
申请号 WO1994US13661 申请日期 1994.12.05
申请人 SCHERING CORPORATION 发明人 TING, PAULINE, C.;FRIARY, RICHARD, J.;TOM, WING, C.;LEE, JOE, F.;SEIDL, VERA, A.
分类号 C07D211/14;A61K31/135;A61K31/165;A61K31/335;A61K31/445;A61K31/451;A61P29/00;A61P37/08;C07C211/31;C07C211/32;C07C215/20;C07C215/38;C07C217/16;C07C217/48;C07C233/05;C07C233/13;C07C235/34;C07D211/70;C07D313/12;(IPC1-7):C07D313/12;A61K31/13 主分类号 C07D211/14
代理机构 代理人
主权项
地址