| 摘要 |
The invention relates to a directly compressible lactitol granulate and lactitol tablets made therefrom. The granulate comprises lactitol and a physiologically acceptable, non-cariogenic binder, which may be a non-cariogenic sugar alcohol, a polymerized reducing sugar, and alkali carboxymethylcellulose, a hydrogenated starch hydrolysate, a hydroxypropylcellulose, a physiologically acceptable cellulose derivative, polyvinylpyrrolidone, gum arabic or another physiologically acceptable gum. The preferred binder is lactitol. The invention also relates to a method of producing a directly compressible lactitol granulate, which can be used in tabletting contexts. The produced tablets exhibit high hardness and low friability. They are non-cariogenic and manifest the taste profile and metabolic properties of lactitol. |
