发明名称 |
Modified bdnf |
摘要 |
Modified BDNF having improved pharmacological activities, pharmacokinetics and physical properties can be obtained by modifying BDNF with a 1-acyl-glycerol derivative. This BDNF being modified with a 1-acyl-glycerol derivative of the present invention has more efficacious and more excellent pharmacokinetic properties with retaining the useful effects being characteristic to BDNF which are useful as remedies for neurodegenerative diseases and diabetes mellitus, and hence, it is particularly useful as a therapeutic agent for treatment of type 2 diabetes mellitus. |
申请公布号 |
AU3417801(A) |
申请公布日期 |
2001.09.12 |
申请号 |
AU20010034178 |
申请日期 |
2001.02.26 |
申请人 |
SUMITOMO PHARMACEUTICALS COMPANY, LIMITED;LTT INSTITUTE CO., LTD. |
发明人 |
RIE IGARASHI;YUTAKA MIZUSHIMA;MUTSUO TAIJI;CHIKAO NAKAYAMA;HIROSHI NOGUCHI |
分类号 |
A61K38/00;A61P3/10;C07K14/475 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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