| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a compound causing physiological cooling effect when applied to the skin or mucosa. <P>SOLUTION: The compound is represented by formula (I), (wherein, R<SP>1</SP>is menthan-3-yl; R<SP>2</SP>is ethylene, propylene, trimethylene, tetramethylene or formula (a); X is O, S or NH; Z is O; Y is hydroxy, a 1-10C alkoxy, a 2-6C acyloxy or mercapto; m and n are each independently an integer of 1-3; and m+n≤4) or formula (II) except formulas (b). <P>COPYRIGHT: (C)2005,JPO&NCIPI |
