发明名称 ANTIHYPOTENSION MEDICATION
摘要 FIELD: chemistry. ^ SUBSTANCE: claimed invention relates to application of compounds of general formula I where R1=H, CH3CO, C2H5CO, CH2=CHCO, CH2=C(CH3)CO, C6H5CO, m-FC6H4CO, m-ClC6H4CO, BrC11H22CO. R2=CH3, C2H5, n-C3H7, i-C3H7, C4H9, C4H8F, C2H4F, C2H4OH, CH2=CH-CH2-, CH2-CH-CH2 X=Cl, Br, I, dialkylphosphate, methane sulfonate, as hypotensive medication. In duration of hypertensive action proposed substances exceed mesatone and other medications, applied in medical practice for hypotensive condition treatment. Also described is pharmacological composition, based on formula I compounds. ^ EFFECT: obtaining of medication, which in duration of action exceeds mesatone and other medications, applied in medical practice for hypotensive condition treatment. ^ 3 cl, 4 tbl, 6 ex
申请公布号 RU2353614(C1) 申请公布日期 2009.04.27
申请号 RU20070140745 申请日期 2007.11.06
申请人 GOSUDARSTVENNOE UCHEBNO-NAUCHNOE UCHREZHDENIE KHIMICHESKIJ FAKUL'TET MOSKOVSKOGO GOSUDARSTVENNOGO UNIVERSITETA IM. M.V. LOMONOSOVA;GOSUDARSTVENNOE UCHREZHDENIE MEDITSINSKIJ RADIOLOGICHESKIJ NAUCHNYJ TSENTR RAMN 发明人 PROSKURJAKOV SERGEJ JAKOVLEVICH;VERKHOVSKIJ JURIJ GRIGOR'EVICH;FILIMONOVA MARINA VLADIMIROVNA;SHEVCHENKO LJUDMILA IVANOVNA;MANDRUGIN ANDREJ ALEKSANDROVICH;TROFIMOVA TAT'JANA PETROVNA;FEDOSEEV VLADIMIR MIKHAJLOVICH
分类号 A61K31/27;A61P9/02;C07C335/32 主分类号 A61K31/27
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