RECOMBINANT VECTORS BASED ON 'LIVE' VIRUS OF FOWL POX AND THEIR APPLICATION IN PHARMACEUTICAL COMPOSITIONS AGAINST VIRUS OF HEPATITIS C

摘要

FIELD: chemistry, biochemistry. ^ SUBSTANCE: invention relates to virology and genetic engineering. Claimed is recombinant virus of fowl pox, inducing immune response against hepatitis C (HCV) virus, containing DNA-fragment obtained from HCV. Said DNA-fragment codes fragment core-E1 polyprotein or chimeric protein, containing HCV epitopes, specific to helper and cytotoxic T-cells. Also claimed is pharmaceutical composition containing such virus. ^ EFFECT: invention can be used in medicine. ^ 9 cl, 8 dwg, 4 ex