Processes for the preparation of rocuronium bromide and intermediates thereof
摘要
A novel process for preparing (2beta,3alpha,5alpha,16beta,17beta)-17-acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl) androstane, a known intermediate in the synthesis of the skeletal muscle relaxant rocuronium bromide, is disclosed.
申请公布号
US7579461(B2)
申请公布日期
2009.08.25
申请号
US20050034510
申请日期
2005.01.13
申请人
CHEMAGIS LTD.
发明人
ADAR ELIEZER;SONDACK DAVID;FRIEDMAN ODED;MANASCU IOSEF;FIZITZKI TAMIR;FREGER BORIS;ARAD ODED;WEISMAN ALEXANDER;KASPI JOSEPH