| 发明名称 |
Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof |
| 摘要 |
Provided are combinations and pharmaceutical compositions comprising bendamustine and a HDAC inhibitor. A preferred HDAC inhibitor is N-hydroxy-4-{ 2-[3-(N,N-dimethylaminomethyl)benzofuran-2-ylcarbonylamino]ethoxy} -benzamide. The combinations and pharmaceutical compositions are useful in the treatment of cancer. |
| 申请公布号 |
NZ621221(A) |
申请公布日期 |
2016.07.29 |
| 申请号 |
NZ20110621221 |
申请日期 |
2011.09.13 |
| 申请人 |
PHARMACYCLICS LLC |
发明人 |
BUGGY JOSEPH J.;MODY TARAK D.;VERNER ERIK J.;PURRO NORBERT;BALASUBRAMANIAN SRIRAM;KLOOS IOANA;DEPIL STÉPHANE;LOURY DAVID J. |
| 分类号 |
A61K31/343;A61K9/14;A61K9/28;A61K31/4184;A61P35/00 |
主分类号 |
A61K31/343 |
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