TARGETING ANTIGEN-SPECIFIC T CELLS FOR SPECIFIC IMMUNOTHERAPY OF AUTOIMMUNE DISEASE

摘要

Antigen-specific T cells are stimulated to proliferate by activation with properly presented antigen. Targeting a detrimental product to only those cells which are stimulated to proliferate in response to the antigen presentation permits the selective and highly efficient ablation of a key component of the disease symptomology of myasthenia gravis.