| 摘要 |
An implantable medical device according to the present invention comprises a body, such as a stent or a wire, and an isotope having a high neutron activation cross section, such as <168>Yb or <124>Xe, ion-implanted onto the surface of the body. The use of isotopes having high neutron activation cross sections allows a wider choice of substrates to be employed, including stainless steel, nickel, titanium, and alloys including these metals, because the time required for neutron activation of the device is reduced. A coating of high-density material may be incorporated to serve several useful purposes, including containment of undesirable beta particles from long-lived radioactive species, creation of a biologically inert surface, and enhancement of x-ray radiopacity to improve the visibility of an implanted medical device. The implantable medical devices of the present invention also comprise radioactive medical devices which include radioisotopes such as <169>Yb and <125>I. |
