发明名称 |
HEPATITIS B VACCINE |
摘要 |
<p>A polypeptide vaccine is disclosed with the amino acide sequence of Asp-Pro-Arg-Val-Arg-Gly-Leu-Try-Phe-Pro-Ala-Gly-Gly-Ser-Ser-Ser-Gly-Thr-Val that bears the receptor for polymerized human serum albumin capable of raising antibodies to inhibit the access and entry of hepatitis B virus (HBV) to hepatocytes. The polypeptide vaccine is also shown in which the 9th amino acid residue (Phe) is replaced by leucine.</p> |
申请公布号 |
EP0171260(B1) |
申请公布日期 |
1991.03.27 |
申请号 |
EP19850305457 |
申请日期 |
1985.07.31 |
申请人 |
NAKAMURA, TETSUO |
发明人 |
NAKAMURA, TETSUO;MACHIDA, ATSUHIKO |
分类号 |
C12N15/09;A61K39/00;A61K39/29;C07K7/08;C07K14/02;C07K14/10;C07K14/18;C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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