| 发明名称 |
METHOD FOR PROLONGING THE EXPRESSION OF A GENE OF INTEREST USING SOLUBLE CTLA4 MOLECULES |
| 摘要 |
The invention provides a method for enhancing the expression of a gene of interest by a cell, the cell (a) comprises a recombinant nucleic acid sequence encoding and (b) is capable of expressing the gene of interest, the method comprising contacting the cell with an amount of a soluble CTLA4 molecule effective to enhance the expression of the gene of interest by the cell.
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| 申请公布号 |
CA2223412(A1) |
申请公布日期 |
1996.12.12 |
| 申请号 |
CA19962223412 |
申请日期 |
1996.06.05 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY;THE UNIVERSITY OF WASHINGTON;THE UNIVERSITY OF WASHINGTON |
发明人 |
ARUFFO, ALEJANDRO A.;WILSON, CHRISTOPHER B.;KAY, MARK A.;LEDBETTER, JEFFREY;LINSLEY, PETER S.;HOLLENBAUGH, DIANE L. |
| 分类号 |
C12N15/09;A61K31/00;A61K35/76;A61K38/00;A61K48/00;A61P37/00;A61P37/02;A61P43/00;C07K14/705;C12N15/86;C12N15/861;C12P21/08;(IPC1-7):A61K48/00;A61K38/17;A61K39/395;A61K31/70 |
主分类号 |
C12N15/09 |
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