The present invention provides a herpes simplex virus strain having a functional ICP27 gene and lacking at least a functional ICP4 gene and a functional ICP34.5 gene. It also provides the use of a herpes simplex virus strain which lacks at least a functional ICP4 gene and a functional ICP34.5 gene in the treatment of disorders of, or injuries to, the nervous system of a mammal.
申请公布号
WO9938955(A3)
申请公布日期
1999.09.23
申请号
WO1999GB00306
申请日期
1999.01.29
申请人
NEUROVEX LIMITED;COFFIN, ROBERT, STUART;LATCHMAN, DAVID, SEYMOUR;FINNIE, NICHOLAS, JAMES
发明人
COFFIN, ROBERT, STUART;LATCHMAN, DAVID, SEYMOUR;FINNIE, NICHOLAS, JAMES