Use of an immunodeficiency-virus suppressing lymphokine (ISL) to inhibit the replication of viruses, in particular of retroviruses

摘要

An isolated polypeptide which inhibits the replication of retroviruses in peripheral blood lymphocytes and i) is encoded by the DNA sequence shown in SEQ ID NO: 1 or complementary sequences; or ii) is encoded by DNA sequences which are degenerate to those of SEQ ID NO: 1 or its complement, and nucleic acids encoding said polypeptide. The protein is useful for inhibition of viral replication.