摘要 |
Synthesis of fluoride derivatives comprises a step in which a substrate consisting of at least one halogen-bearing sp3-hybridised C atom with at least two halogens, one being of atomic number greater than that of F (this halogen-bearing C being attached to at least one atom of low hybridisation with an unsaturation), is reacted with a compound associated with a Bronsted base having a defined number n of HF molecules (n = 3 - 20, preferably 15 and more preferably 10).The process excludes halogen-bearing C atoms attached to chalcogens. |