| 摘要 |
<p>Amide derivatives represented by general formula [1] or pharmaceutically acceptable salts thereof, and drug compositions containing both as the active ingredient: (wherein R?1 and R2¿ are each independently hydrogen, optionally substituted alkyl, acyl, optionally substituted aryl, or an optionally substituted aromatic heterocyclic group; R?3, R4, R5 and R6¿ are each independently hydrogen, halogeno, hydroxyl, optionally substituted amino, optionally substituted alkyl, alkoxy, nitro, or the like; and R7 is optionally substituted cyclic amino or optionally substituted azabicycloalkylamino). The above compounds are useful as TGF-β production inhibitors or TGF-β antagonists.</p> |
