发明名称 NOVEL INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)
摘要 <p>A compound having the structure set forth in Formula (I): wherein the variables Y, R1, R2, R3, R4 and R5 are as defined herein. Compounds described herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of such compounds and pharmaceutical compositions to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.</p>
申请公布号 WO2009029375(A1) 申请公布日期 2009.03.05
申请号 WO2008US71622 申请日期 2008.07.30
申请人 LEAD THERAPEUTICS, INC.;CHU, DANIEL 发明人 CHU, DANIEL
分类号 A61K31/501;A61K31/16;C07D401/10;C07D403/10 主分类号 A61K31/501
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