发明名称 METHOD OF PREPARING TUBERCULOSIS ANATOXIN
摘要 FIELD: veterinary medicine. SUBSTANCE: invention is designed for specific prophylactics of animal infection diseases. Tuberculosis mycobacteria are grown and then destroyed. To that end, formalin is added to culture liquid in two steps: first to formalin concentration 0.3-0.4%, after which mixture is incubated for 7-10 days at 37-40 C, and then to final formalin concentration 0.5-0.6%, after which incubation at 44-46 C is carried out for 5-8 days. Destruction of mycobacteria is effected by <SP>60</SP>Co gamma- radiation in dose (1.0-2.0) x 10 R. When detoxification of culture liquid is completed, aluminum hydroxide is added. Resulting mixture is centrifuged or settled, precipitate is collected, bagged, and autoclaved. EFFECT: increased anatoxin storage time to 3-5 years. 2 cl, 4 ex
申请公布号 RU2139090(C1) 申请公布日期 1999.10.10
申请号 RU19990100826 申请日期 1999.01.26
申请人 ZAKRYTOE AKTSIONERNOE OBSHCHESTVO "AGROBIZNESTSENT 发明人 EVGLEVSKIJ A.A.
分类号 A61K39/04;C12N1/06;C12N13/00;C12R1/32;(IPC1-7):A61K39/04 主分类号 A61K39/04
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