发明名称 Electrospun dextran fibers and devices formed therefrom
摘要 The invention generally relates to dextran fibers which are preferably electrospun and devices formed from such fibers. In particular, such devices may include substances of interest (such as therapeutic substances) associated with the electrospun fibers. Upon exposure to a liquid the electrospun fibers dissolve immediately and the substances of interest are released into the liquid. Exemplary devices include bandages formed from electrospun dextran fibers and associated agents that promote hemostasis, such as thrombin and fibrinogen.
申请公布号 US9399082(B2) 申请公布日期 2016.07.26
申请号 US200912937322 申请日期 2009.04.10
申请人 The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.;Virginia Commonwealth University 发明人 Bowlin Gary L.;Simpson David G.;Bowman James R.;Rothwell Stephen W.
分类号 A61K9/00;A61L15/44;A61F13/00;A61L15/28;A61L15/32;D01D5/00;D01F1/10;D01F6/92;D01F9/00 主分类号 A61K9/00
代理机构 Fish & Richardson P.C. 代理人 Fish & Richardson P.C.
主权项 1. A bandage consisting of a mat consisting of: electrospun dextran fibers consisting of water-soluble dextran and water, wherein the electrospun dextran fibers are configured to dissolve within three minutes after contact with a bodily fluid; and dry particles comprising thrombin and dry particles comprising fibrinogen.
地址 Rockville MD US