Cells transformed to express on their surface a component which binds to an Fc receptor of an effector cell are disclosed. Also disclosed are expression vectors used to transform the cells. Once transformed, the cells bind to effector cells via the Fc receptor of the effector cell to stimulate an effector cell mediated immune response.
申请公布号
WO9928349(A3)
申请公布日期
1999.11.18
申请号
WO1998US25556
申请日期
1998.12.02
申请人
MEDAREX, INC.;KELER, TIBOR;GOLDSTEIN, JOEL;GRAZIANO, ROBERT;DEO, YASHWANT, M.
发明人
KELER, TIBOR;GOLDSTEIN, JOEL;GRAZIANO, ROBERT;DEO, YASHWANT, M.