发明名称 |
Antibodies to myeloid progenitor inhibitory factor-1 (MPIF-1) |
摘要 |
There are disclosed therapeutic compositions and methods using isolated nucleic acid molecules encoding a human myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptide (previously termed MIP-3 and chemokine beta8 (CKbeta8 or ckb-8)); a human monocyte-colony inhibitory factor (M-CIF) polypeptide (previously termed MIP1-gamma and chemokine beta1(CKbeta1 or ckb-1)), and a macrophage inhibitory protein-4 (MIP-4), as well as MPIF-1, M-CIF and/or MIP-4 polypeptides themselves, as are vectors, host cells and recombinant methods for producing the same.
|
申请公布号 |
US7364865(B2) |
申请公布日期 |
2008.04.29 |
申请号 |
US20060381977 |
申请日期 |
2006.05.05 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
GENTZ REINER L.;KREIDER BRENT L.;ZHANG JUN;ANTONACCIO MICHAEL;MENDRICK DONNA;JIMENEZ PABLO;PATEL VIKRAM;ROSEN CRAIG A.;ADAMS MARK D.;LI HAODONG;RUBEN STEVEN M. |
分类号 |
C12N5/10;A61K38/00;A61K48/00;C07K1/113;C07K1/36;C07K14/50;C07K14/52;C07K16/24;C12N5/12;C12N15/19;C12N15/72;G01N33/53 |
主分类号 |
C12N5/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|