PROCESS FOR PREPARING 3-ARYLSULFUR HYDROXAMIC ACIDS

摘要

This invention provides processes for the preparation of a compound of formula I: Y-C(=O)-C(R1)(R2)-CH2-S(O)nR3 wherein: Y is hydroxy or XONX, where each X is independently hydrogen, lower alkyl or lower acyl; R1 is hydrogen or lower alkyl; R2 is hydrogen, lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, or R1 and R2 together with the carbon atom to which they are attached form a cycloalkyl or heterocyclo group; and R3 is aryl. The invention also provides novel aryl haloalkyl sulfide and aryl alkyl sulfide intermediates useful for the preparation of compounds of formula I and novel processes of preparing aryl alkyl sulfides.