发明名称 |
PROCESS FOR THE PREPARATION OF A-ETHYNYL BENZOPHENONES |
摘要 |
The invention is a new process for the preparation of ringsubstituted .alpha.-ethynyl-benzhydrol derivatives thereof by reacting the corresponding benzophenone derivative with acetylene in an aprotic, in the presence of an alkali metal tertiary alcoholate, preferably potassiumtert.-butylate or potassium-tert.-amylate. Also new substituted derivatives of .alpha.-ethynyl-benzophenone are prepared by the invention. These compounds exert a blocking or inducing effect on the microsomal enzyme system of the liver and also possess antiviral and fungicidal properties. They are also valuable starting materials in the synthesis of other biologically active compounds. |
申请公布号 |
CA1039309(A) |
申请公布日期 |
1978.09.26 |
申请号 |
CA19740207026 |
申请日期 |
1974.08.14 |
申请人 |
RICHTER GEDEON VEGYESZETI GYAR RT |
发明人 |
TOTH, EDIT;TOERLEY, JOZSEF;GOEROEG, SANDOR;SZPORNY, LASZLO;PALOSI, EVA;SZEBERENYI, SZABOLCS |
分类号 |
C07C43/23;A61K31/135;A61P31/12;C07C27/00;C07C27/18;C07C29/42;C07C33/025;C07C33/04;C07C33/042;C07C33/28;C07C41/00;C07C49/175;C07C67/00;C07C201/00;C07C213/00;C07C215/68;C07C217/18;C07C231/00;C07C231/12;C07C233/67;(IPC1-7):07C33/00;07C91/00;07C103/75 |
主分类号 |
C07C43/23 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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