发明名称 |
Enantiomeric enrichment and stereoselective synthesis of chiral amines |
摘要 |
Amines in which the amino group is on a secondary carbon atom which is chirally substituted can be enantiomerically enriched by the action of an omega-amino acid transaminase which has the property of preferentially converting one of the two chiral forms to a ketone. The process also can be used to stereoselectively synthesize one chiral form from ketones substantially to the exclusion of the other. |
申请公布号 |
IE902159(A1) |
申请公布日期 |
1991.01.02 |
申请号 |
IE19900002159 |
申请日期 |
1990.06.14 |
申请人 |
CELGENE CORPORATION |
发明人 |
DAVID L. STIRLING;ANDREW L. ZEITLIN;GEORGE W. MATCHAM |
分类号 |
C07C209/00;C12N9/10;C12P7/26;C12P41/00 |
主分类号 |
C07C209/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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