发明名称 AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS
摘要 The present invention relates to a novel thrombin inhibitor which is effective even when orally administered. More specifically, the present invention relates to an aromatic amidine derivative represented by formula (I) and the salts thereof, which show potent selective inhibitory activity for thrombin in which (a), R, R<1>, R<2>, R<3>, A, W, Y and n are defined as described in the specification.
申请公布号 WO9745424(A1) 申请公布日期 1997.12.04
申请号 WO1997KR00100 申请日期 1997.05.31
申请人 C & C RESEARCH LABORATORIES;KOO, BON, AM;MIN, JAE, KI;HONG, WOO, SANG;RYU, EUN, JUNG;NAM, WOONG, HYUN;KIM, JONG, MIN 发明人 KOO, BON, AM;MIN, JAE, KI;HONG, WOO, SANG;RYU, EUN, JUNG;NAM, WOONG, HYUN;KIM, JONG, MIN
分类号 C07D401/06;A61K31/00;A61K31/40;A61K31/4025;A61K31/403;A61K31/404;A61K31/415;A61K31/4164;A61K31/4184;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61K31/4465;A61K31/4523;A61K31/454;A61K31/47;A61K31/472;A61K31/4725;A61P7/00;A61P7/02;C07D207/08;C07D401/14;C07D403/06;C07D403/14;C07D405/06;C07D405/14;C07D409/06;C07D409/14 主分类号 C07D401/06
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